Abstract
The short comparative genomic hybridization (short-CGH) method was used to perform a comprehensive cytogenetic study of isolated blastomeres from advanced maternal age embryos, discarded after fluorescent in situ hybridization (FISH) preimplantation genetic screening(PGS), detecting aneuploidies (38.5% of which corresponded to chromosomes not screened by 9-chromosome FISH), structural aberrations (31.8%), and mosaicism (77.3%). The short-CGH method was subsequently applied in one PGS, achieving a twin pregnancy.
Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Year: 2010
Journal: Fertility and sterility
PMID: 20797709
Centers: Congratulations to Aina Nicolau for defending her Master’s Thesis New publication in Molecular Human Reproduction New publication in the Journal of Assisted Reproduction and Genetics Agustina Alessandroni has joined our laboratory to pursue her PhD degree.