Early ovarian hyperstimulation syndrome is completely prevented by gonadotropin releasing-hormone agonist triggering in high-risk oocyte donor cycles: a prospective, luteal-phase follow-up study.

Abstract

In this prospective, follow-up study of 102 high-risk oocyte donors in their luteal phase, we found a complete absence of ovarian hyperstimulation syndrome (no signs of hemoconcentration or ascites) after the donors were triggered with a gonadotropin releasing-hormone (GnRH) agonist. Due to its powerful preventive effect, the GnRH antagonist protocol combined with a GnRH agonist trigger should preferentially be used in egg donors; in conjunction with an effective luteal support or embryo cryopreservation, the protocol could also be applied to high-risk in vitro fertilization patients.

Year: 2009

Journal: Fertility and sterility

PMID: 19800620

Centers: Congratulations to Aina Nicolau for defending her Master’s Thesis , New publication in Molecular Human Reproduction , New publication in the Journal of Assisted Reproduction and Genetics , Agustina Alessandroni has joined our laboratory to pursue her PhD degree. ,